GK Quiz on Human Metapneumovirus (HMPV), Questions and Answers

Human Metapneumovirus (hMPV) is a virus that affects the respiratory system, causing illnesses like colds, bronchitis and pneumonia. It was first discovered in 2001 and mainly impacts children, older adults and people with weak immune systems. The virus spreads through coughing, sneezing or touching infected surfaces. Here is a quiz to test your knowledge about this important health topic!

An Overview of Human Metapneumovirus

Human Metapneumovirus (HMPV) is a virus with single-stranded RNA, belonging to the Pneumoviridae family, and is related to the Avian Metapneumovirus (AMPV). It was first discovered in 2001 in the Netherlands using advanced PCR techniques. By 2016, it became the second leading cause of respiratory illnesses in children under 5 years old, after Respiratory Syncytial Virus (RSV), affecting healthy young children in the United States.

GK Quiz on Human Metapneumovirus

A General Knowledge (GK) quiz on Human Metapneumovirus (HMPV) helps to explore key facts about this respiratory virus, including its discovery, structure, symptoms and global significance.

Q1. What type of virus is Human Metapneumovirus (HMPV)?

(a) Positive-sense RNA virus

(b) Negative-sense RNA virus

(c) DNA virus

(d) Retrovirus

S1. Ans. (b)

Q2. To which family does HMPV belong?

(a) Coronaviridae

(b) Pneumoviridae

(c) Paramyxoviridae

(d) Orthomyxoviridae

S2. Ans. (c)

Q3. In which year was HMPV first discovered?

(a) 1998

(b) 2001

(c) 2005

(d) 2010

S3. Ans. (b)

Q4. Where was HMPV first isolated?

(a) United States

(b) Netherlands

(c) China

(d) Australia

S4. Ans. (b)

Q5. HMPV is closely related to which other virus?

(a) Respiratory syncytial virus (RSV)

(b) Influenza virus

(c) Avian metapneumovirus (AMPV)

(d) Adenovirus

S5. Ans. (c)

Q6. Which protein is responsible for HMPV attachment to host cells?

(a) F protein

(b) G protein

(c) M protein

(d) N protein

S6.  Ans. (a)

Q7. What kind of genome does HMPV have?

(a) Circular DNA

(b) Single-stranded RNA

(C) Double-stranded RNA

(d) Linear DNA

S7. Ans. (b)

Q8. What does the F protein of HMPV bind to in host cells?

(a) Integrinαvβ1

(b) Heparan sulfate

(c) Glycosaminoglycans

(d) Collagen

S8. Ans. (b)

Q9. Which molecular biology technique revealed the relationship between HMPV and AMPV?

(a) Gel electrophoresis

(b) RAP-PCR

(c) Western blot

(d) CRISPR

S9. Ans. (b)

Q10. HMPV fusion events occur at which pH level?

(a) Neutral pH

(b) Acidic pH

(c) Basic pH

(d) Variable pH

S10. Ans. (b)