Indian Institute of Technology Madras Researchers has developed an Artificial Intelligence-based Mathematical Model called ‘NBDriver’ to identify cancer-causing alterations in cells. The algorithm uses a relatively unexplored technique of leveraging DNA composition to pinpoint genetic alterations responsible for cancer progression, which is difficult using present methodologies. Understanding the underlying mechanism of these alterations will help identify the most appropriate treatment strategy for a patient in an approach known as ‘precision oncology’.
About the Cancer:
- Cancer is caused due to the uncontrolled growth of cells driven mainly by genetic alterations.
- In recent years, high-throughput DNA Sequencing has revolutionized the area of cancer research by enabling the measurement of these alterations.
- However, due to the complexity and size of these sequencing datasets, pinpointing the exact changes from the genomes of cancer patients is notoriously difficult.